Answer: UltraGRO™ is manufactured in our Atlanta, GA facility from human platelet units obtained from FDA-registered or HC-registered blood banks in North American. Donors are carefully selected, platelets are fully screened by the blood banks, and then processed by Helios’ proprietary methods and stringent quality standards, then passed through a 0.2 μm filter to produce and fill a sterile bottled product. UltraGRO™ release criteria include testing for endotoxin, mycoplasma and sterility. A Certificate of Analysis (CoA) is provided with each product shipped from every production lot.
Is a GMP-grade UltraGRO™ available?
Answer: Yes. UltraGRO™ is available as a GMP product. As regulatory requirements for ancillary materials differ from region-to-region, it is best to discuss your GMP needs with Helios prior to purchasing GMP UltraGRO™.
How long can frozen UltraGRO™ be stored?
Answer: UltraGRO™ is stable for 2.5 years from the date of manufacture when stored properly at -20°C. Uninterrupted frozen storage at -20°C for 2.5 years does not decrease UltraGRO™ performance in cell culture. However, interrupted storage or storage at higher temperatures may affect results. We anticipate that our ongoing studies will indicate that the shelf life of UltraGRO™ is longer than 2.5 years.
What other cell types can be grown in UltraGRO™?
Answer: UltraGRO™ has been used for culturing natural killer (NK) cells, cytokine-induced killer (CIK) cells, and CD3⁺CD8⁺ T cells with success. Third party publications have reported replacement of FBS and serum-free supplements with hPL for successful expansion of other cell lines, including: fibroblast, CHO cells, corneal epithelial cells, endothelial cell lines, and some cancer cell lines (such as K562, Jurkat, HeLa, and MCF-7)